Pharmaceutical preparations and substances; preparations and substances for medical, therapeutic or prophylactic use; naturopathic, probiotic, synbiotic, and heat-killed/postbiotic microbial preparations and substances; dietetic preparations and substances; dietary supplements; intravaginal and intrarectal suppositories; food additives and supplements for medical, therapeutic, or prophylactic use; nutrients and nutritional preparations, substances, food additives for human use; probiotic formulations, namely, suppositories and lyophilized powders for medical purposes, in particular, for producing beneficial metabolites, modulating inflammation, increasing beneficial microbes, and inhibiting pathogens in the human microbiome; probiotic, prebiotic, synbiotic, and heat-killed/postbiotic formulations, namely, capsules, chewable tablets, gummies, suppositories, and lyophilized powders for the gut microbiome of children and adolescents, for supporting healthy vaginal microbiomes in premenarchial and postmenarchial females, and for increasing strains of beneficial bacteria in children and adolescents; pharmaceutical preparations for microbiome dysbiosis resulting from the use of antibiotic medications and consumer health interventions for the restoration of balance to a perturbed human microbiome.;